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Jess_ica
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« on: August 21, 2006, 01:28:44 AM »

Hi,
I was wondering if anyone would be able to give me a good explanation on how photophobia occurs. Particularly in meningitis or migraines.
Thanks
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shashikiran
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« Reply #1 on: August 26, 2006, 02:04:21 AM »

Hello Jessica,

Photophobia is a term used to describe light sensitivity or abnormal intolerance to light. Patients with photophobia avoid light because of pain or discomfort. It is generally seen in diseases affecting the iris and anterior segment of the eye. However, photophobia may also be seen in patients with completely normal appearing anterior segments (including blepharospasm, sub-arachnoid hemorrhage and head injury apart from migraine and meningitis that you have mentioned).

The mechanism of photophobia is not very well understood, but is thought to involve the trigeminal pathway with possible input from the occipital lobe and thalamus. Irritation to any region supplied by the trigeminal nerve can result in photophobia. This is all that is currently know about the mechanism of photophobia.

Hope this helps...
Sorry for the delay in replying,
shashikiran
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Jess_ica
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« Reply #2 on: August 27, 2006, 11:37:34 PM »

thankyou for the help. its clearer to me now.
Jess
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medstudent
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« Reply #3 on: August 31, 2006, 08:13:31 AM »

This information was useful to me also...

Thanks for this Smiley
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backham
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« Reply #4 on: August 13, 2008, 09:30:35 AM »

There was no difference in the duration of surgery comparing test eyes given intracameral lidocaine with control eyes given sterile saline (P = 0.81). There was no significant difference in the level of pain reported when comparing test eyes given intracameral lidocaine with control eyes (P = 1.00). None of the patients reported any significant difference in photophobia between their two eyes (P = 1.00). When comparing ERG measurements, test eyes given intracameral lidocaine did not show any significant decrease in ERG amplitudes or prolonged latencies compared with control eyes. When comparing VER measurements, test eyes given intracameral lidocaine did not show any increase in P1 latencies compared with control eyes (P = 0.31). When evaluating all postoperative ERG results 1 day after surgery, there was a suggestion of improved cone function.
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