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1. A 17 year old boy has presented with facial puffiness for the last 1 week. He has also noticed mild reddish discoloration of his urine. On enquiring, he admits to having had an episode of sore throat about 3 weeks back. On examination, he has facial puffiness and mild pedal edema. His blood pressure is 140/96 mmHg. What is the diagnosis? Justify your diagnosis and explain the pathophysiological basis for his symptoms and signs. How will you manage this patient? 2. A 25 year old lady has been admitted with anasarca. She complains of generalized weakness, occasional mild fever and body ache for the last 3 to 4 months and progressively increasing swelling for the last 2 weeks. On examination, she is found to have symmetrical rashes on her face under the eyes and on the nose. Her blood pressure is 130/76 mmHg. She has pedal edema and ascites. There are no other significant findings. What is the diagnosis? Justify your diagnosis and explain the pathophysiological basis for his symptoms and signs. How will you manage this patient? 3. A 65 year old man has developed oliguria for last 3 days. He also complains of sleeplessness and malaise. He has episodes of similar symptoms for about 1 year. On examination, he is very pale and his blood pressure is 180/100 mmHg. There is mild pedal edema. What is the diagnosis? Justify your diagnosis and explain the pathophysiological basis for his symptoms and signs. How will you manage this patient? 4. A 54 year old known diabetic man also has hypertension and ischemic heart disease. He has diabetes for about 10 years. He is asymptomatic. On routine evaluation, his urine showed presence of about 120mg of albumin/24 hr. What is the diagnosis? Justify your diagnosis and explain the pathophysiological basis for his symptoms and signs. How will you manage this patient?
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